Description

11-Cis Retinoic Acid is a specific geometric isomer of retinoic acid, a critical signaling molecule derived from vitamin A. This high-purity compound is essential for research and development in advanced life sciences, particularly in the study of visual biochemistry and cellular differentiation pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of high-value biochemical reagents.

Application

• Biochemical Research: A key reference standard and active agent in studies of the visual cycle, particularly involving rhodopsin and phototransduction.
• Pharmaceutical Development: Serves as a critical intermediate or reference compound in the development of novel retinoid-based therapies for dermatological and oncological conditions.
• Cell Biology Studies: Used to investigate the role of specific retinoid isomers in cellular differentiation, proliferation, and apoptosis.
• Analytical Standard: Employed as a high-purity calibration standard in HPLC, LC-MS, and other analytical methods for quantifying retinoids in complex matrices.
• Nutraceutical Research: Studied for its potential biological activity and metabolic pathways in advanced nutritional science projects.

Basic Information

Product Name	11-Cis Retinoic Acid
CAS No.	68070-35-9
Molecular Formula	C₂₀H₂₈O₂
Molecular Weight	300.44 g/mol
Synonyms	(11Z)-Retinoic Acid; 11-Z-Retinoic Acid; all-trans-Retinoic Acid Isomer; Vitamin A Acid Isomer; (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic Acid; 11-cis-Vitamin A Acid
EINECS	Contact for details

Quality Control

Our 11-Cis Retinoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). Allow the sealed container to reach room temperature before opening to minimize condensation and exposure. The material is light-sensitive and easily oxidized.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in DMSO, ethanol; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.