Description

2-Cyano-3-(4-Fluorophenyl)-2-Propenethioamide is a specialized organic intermediate featuring a cyano group and a thioamide moiety on a propenyl backbone substituted with a fluorophenyl ring. This unique molecular architecture makes it a valuable building block for synthesizing complex heterocyclic compounds and functional materials. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the thioamide and fluorinated aromatic system.
• Heterocyclic Chemistry: Serves as a versatile substrate for constructing nitrogen and sulfur-containing heterocycles like thiazoles, pyridines, and their fused derivatives.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or optical properties.
• Chemical Synthesis: Employed in organic synthesis as a Michael acceptor or a dipolarophile in cycloaddition reactions to increase molecular complexity.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical reactions and pathways.

Basic Information

Product Name	2-Cyano-3-(4-Fluorophenyl)-2-Propenethioamide
CAS No.	68029-40-3
Molecular Formula	C10H7FN2S
Molecular Weight	206.24 g/mol
Synonyms	2-Propenethioamide, 2-cyano-3-(4-fluorophenyl)-; (2E)-2-Cyano-3-(4-fluorophenyl)prop-2-enethioamide; 3-(4-Fluorophenyl)-2-cyano-2-propenethioamide; 4-Fluorocinnamonitrile thioamide; α-Cyano-4-fluorocinnamothioamide; (E)-2-Cyano-3-(4-fluorophenyl)acrylthioamide
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-(4-Fluorophenyl)-2-Propenethioamide is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.