Description

5-Nitro-1H-Pyrrole-2-Carbonitrile is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and nitrile groups on a pyrrole core, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Research: Acts as a monomer or functional unit in the creation of specialized polymers, dyes, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	5-Nitro-1H-Pyrrole-2-Carbonitrile
CAS No.	67903-53-1
Molecular Formula	C5H3N3O2
Molecular Weight	137.10 g/mol
Synonyms	5-Nitro-1H-pyrrole-2-carbonitrile; 2-Cyano-5-nitropyrrole; 5-Nitro-2-cyanopyrrole; 5-Nitro-2-pyrrolecarbonitrile; 1H-Pyrrole-2-carbonitrile, 5-nitro-; 5-Nitro-pyrrole-2-carbonitrile; 5-Nitropyrrole-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Nitro-1H-Pyrrole-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.