Description

Sodium (6R-Trans)-3-(Acetoxymethyl)-7-[(3,5-Dichloro-4-Oxo-1(4H)-Pyridyl)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is a high-purity sodium salt derivative of a cephalosporin antibiotic intermediate. This compound is critical for ensuring the quality and efficacy of final active pharmaceutical ingredients (APIs) in the synthesis of advanced β-lactam antibiotics. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of next-generation antibacterial agents.

Application

• Key Intermediate in the synthesis of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development for creating novel antibacterial compounds.
• Active Pharmaceutical Ingredient (API) Manufacturing for final drug formulation.
• Reference Standard for quality control and analytical method development in QC/QA laboratories.
• Process Chemistry for scaling up antibiotic production under GMP conditions.

Basic Information

Product Name	Sodium (6R-Trans)-3-(Acetoxymethyl)-7-[(3,5-Dichloro-4-Oxo-1(4H)-Pyridyl)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
CAS No.	67763-91-1
Molecular Formula	C20H16Cl2N3NaO8S
Molecular Weight	552.32 g/mol
Synonyms	Sodium Cefcapene Pivoxil Intermediate; Cefcapene Sodium Salt Derivative; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt (related); Cefcapene Pivoxil Precursor; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Derivative; Antibiotic Intermediate 67763-91-1; Sodium 3-(Acetoxymethyl)-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (structural variant).
EINECS	Contact for details

Quality Control

Our Sodium (6R-Trans)-3-(Acetoxymethyl)-7-[(3,5-Dichloro-4-Oxo-1(4H)-Pyridyl)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity pharmaceutical-grade standards, with specifications aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.