Description

Acth (2-24) (Human, Bovine, Rat) is a synthetic peptide fragment corresponding to the first 24 amino acids of the Adrenocorticotropic Hormone (ACTH). This high-purity research-grade peptide is critical for studying the structure-activity relationships of ACTH and its role in stimulating corticosteroid production. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, neuroscience, and peptide-based therapeutic development.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating the hypothalamic-pituitary-adrenal (HPA) axis, stress response, and corticosteroid synthesis.
• Pharmaceutical Development: Serves as a key intermediate and pharmacological tool in the discovery and development of novel ACTH analogs and related peptide therapeutics.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays (e.g., ELISA, RIA) designed to measure ACTH levels in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study receptor binding, signal transduction pathways, and the physiological effects of ACTH stimulation.
• Neuroscience Research: Investigated for its potential neuromodulatory and behavioral effects beyond its classical endocrine functions.

Basic Information

Item	Details
Product Name	Acth (2-24) (Human, Bovine, Rat)
CAS No.	67654-32-4
Molecular Formula	C₁₃₆H₂₁₀N₄₀O₃₉S
Molecular Weight	2933.4 g/mol
Synonyms	ACTH (2-24); Adrenocorticotropic Hormone (2-24); Corticotropin (2-24); Cosyntropin fragment (2-24); Tetracosactide fragment; Synacthen fragment; 1-24-Corticotropin (fragment 2-24); [Ser¹]-ACTH (2-24)
EINECS	Contact for details

Quality Control

Our Acth (2-24) (Human, Bovine, Rat) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and residual solvent levels are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.