Description

4-(3-(Trifluoromethyl)Phenyl)Butan-2-One is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethylphenyl moiety, enabling the development of novel compounds with enhanced stability and performance. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Modification: Incorporated into polymer chains to alter thermal stability, chemical resistance, and optical properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for studying new fluorination reactions and catalytic processes.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex aromatic molecules with specific olfactory profiles.

Basic Information

Product Name	4-(3-(Trifluoromethyl)Phenyl)Butan-2-One
CAS No.	67646-72-4
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-2-butanone; 3'-Trifluoromethylbutyrophenone; 2-Butanone, 1-[3-(trifluoromethyl)phenyl]-; 4-(3-Trifluoromethylphenyl)butan-2-one; 3-Trifluoromethylbutyrophenone; α-Methyl-3-(trifluoromethyl)phenethyl ketone; 3-(Trifluoromethyl)phenethyl methyl ketone
EINECS	Contact for details

Quality Control

Our production of 4-(3-(Trifluoromethyl)Phenyl)Butan-2-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and reliability for your critical syntheses. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support custom purity requirements to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.