Description

n-Propionylprocainamide is a key chemical intermediate and reference standard of significant interest in pharmaceutical research and development. This compound is primarily valued for its role in the synthesis and analytical profiling of procainamide derivatives, which are critical in cardiac pharmacology. It is essential for researchers and manufacturers in the pharmaceutical industry, particularly those focused on cardiovascular drug development, metabolite studies, and quality control laboratories requiring high-purity analytical standards.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of procainamide and its related analogs for cardiovascular applications.
• Analytical Reference Standard: Used as a high-purity standard in HPLC, LC-MS, and other chromatographic methods for the quantification and identification of procainamide and its metabolites in biological matrices.
• Metabolite Research: Employed in pharmacokinetic and metabolic pathway studies to understand the biotransformation of procainamide.
• Quality Control & Assurance: Essential for in-house method development, validation, and routine quality testing in API (Active Pharmaceutical Ingredient) manufacturing facilities.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for preclinical research and investigative toxicology.

Basic Information

Product Name	n-Propionylprocainamide
CAS No.	67635-46-5
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	N-Propionylprocainamide; Procainamide N-Propionate; N-Acetylprocainamide Propionate Derivative; 4-Amino-N-[2-(diethylamino)ethyl]benzamide propionate; N-(2-Diethylaminoethyl)-4-aminobenzamide propionyl ester; PAAPA (Propionyl Analog of Acetylprocainamide); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-Propionylprocainamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.