Description

1H-Isoindole, 2,3,3A,4,5,7A-Hexahydro-2-(Trifluoroacetyl)- (9Ci) is a specialized heterocyclic building block featuring a fused isoindole core modified with a trifluoroacetyl group. This compound matters for its role as a key synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents, where its unique structure enables the introduction of desirable physicochemical properties. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and fluorine-containing compounds.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials that require specific fluorinated motifs.
• Chemical Biology Probe Development: Utilized to create labeled compounds or molecular probes for studying biological pathways and enzyme interactions.

Basic Information

Item	Details
Product Name	1H-Isoindole, 2,3,3A,4,5,7A-Hexahydro-2-(Trifluoroacetyl)- (9Ci)
CAS No.	67547-14-2
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	2-(Trifluoroacetyl)-2,3,3a,4,5,7a-hexahydro-1H-isoindole; Hexahydro-2-(trifluoroacetyl)-1H-isoindole; 1H-Isoindole, hexahydro-2-(trifluoroacetyl)-; 67547-14-2; 2,3,3a,4,5,7a-Hexahydro-2-(trifluoroacetyl)-1H-isoindole; 2-(Trifluoroacetyl)hexahydro-1H-isoindole
EINECS	Contact for details

Quality Control

Our 1H-Isoindole, 2,3,3A,4,5,7A-Hexahydro-2-(Trifluoroacetyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality systems are designed to support cGMP compliance for applications requiring the highest standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen) after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.