Description

Preproparathormone CAS NO 67418-29-5 is a key peptide precursor in the biosynthesis of parathyroid hormone (PTH), a critical regulator of calcium and phosphate homeostasis. This high-purity biochemical is essential for advanced research and development in endocrinology and metabolic bone disease studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on hormone pathways and related therapeutic targets.

Application

• Pharmaceutical Research & Development: As a critical precursor in the PTH synthesis pathway for investigating hormone regulation and developing novel therapeutics for conditions like hypoparathyroidism and osteoporosis.
• Biochemical Assay Development: Used as a reference standard or key component in the development of immunoassays (ELISA, RIA) to measure PTH or its related metabolites.
• Academic & Clinical Studies: Serves as a vital tool for fundamental research into calcium metabolism, bone biology, and the molecular mechanisms of parathyroid gland function.
• Diagnostic Manufacturing: Employed in the production and calibration of diagnostic kits for measuring PTH levels in clinical settings.
• Peptide Synthesis & Characterization: Acts as a substrate or intermediate for studying peptide processing enzymes or for the synthesis of related peptide analogs.

Basic Information

Product Name	Preproparathormone
CAS No.	67418-29-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Prepro-PTH; Parathyroid Hormone Precursor; Pre-Pro-Parathyroid Hormone; Preproparathyroid Hormone; PTH(1-115) (referring to the prepro form); Parathormone Precursor
EINECS	Contact for details

Quality Control

Our Preproparathormone is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) documenting purity, peptide content, and biological activity (where applicable) is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Assessed by in-vitro assay (Data on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.