Description

H-D-Ala-D-Leu-Oh is a synthetic dipeptide composed of D-alanine and D-leucine residues. This compound is a crucial chiral building block in advanced pharmaceutical research and peptide synthesis, offering high stereochemical purity for developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based drugs, antimicrobial peptides, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or building block in studying enzyme-substrate interactions, peptide stability, and structure-activity relationships (SAR).
• Antimicrobial Peptide Development: Serves as a component in the design and synthesis of new antimicrobial peptides (AMPs) with potential therapeutic applications.
• Protease Inhibitor Synthesis: Employed in the creation of specific peptide sequences that act as inhibitors for targeted proteases.
• Peptide Library Construction: A valuable component for solid-phase or solution-phase synthesis to create diverse peptide libraries for high-throughput screening.
• Diagnostic Reagent Development: Used in the formulation of specialized reagents and conjugates for diagnostic assays and imaging.

Basic Information

Product Name	H-D-Ala-D-Leu-Oh
CAS No.	67392-69-2
Molecular Formula	C9H18N2O3
Molecular Weight	202.25 g/mol
Synonyms	H-D-Ala-D-Leu-OH; D-Alanyl-D-leucine; (R)-2-((R)-2-Aminopropanamido)-4-methylpentanoic acid; D-Ala-D-Leu; DADL; Ala-Leu (D,D-isomer); UNII-8T9Q5O8Y2H
EINECS	Contact for details

Quality Control

Our H-D-Ala-D-Leu-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral HPLC to confirm stereochemical integrity, ensuring compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.