Description

5-Butyrylamino-n-Pentyl-2,4,6-Triiodoisophthalamic Acid Sodium Salt is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its molecular structure, featuring a triiodinated aromatic core, is critical for imparting the high radiopacity required in diagnostic imaging agents. This high-purity intermediate is essential for pharmaceutical manufacturers and advanced research facilities developing next-generation non-ionic, low-osmolar contrast agents to improve patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: Primary building block for synthesizing non-ionic X-ray contrast media like iopamidol, iohexol, and ioversol.
• Diagnostic Imaging Research: Used in R&D for developing novel iodinated contrast agents with enhanced safety profiles and pharmacokinetics.
• Contrast Media Production: Critical raw material in the commercial-scale manufacturing of injectable contrast solutions for computed tomography (CT) and angiography.
• Chemical Synthesis: Serves as a precursor for further chemical modifications to create derivatives with specific binding or clearance properties.
• Quality Control Reference: Employed as a reference standard in analytical laboratories for method development and impurity profiling of final drug products.

Basic Information

Product Name	5-Butyrylamino-n-Pentyl-2,4,6-Triiodoisophthalamic Acid Sodium Salt
CAS No.	67292-85-7
Molecular Formula	C16H19I3N2O4Na
Molecular Weight	755.94 g/mol
Synonyms	5-(Butyrylamino)-N-pentyl-2,4,6-triiodoisophthalamic Acid Sodium Salt; Sodium 5-(Butyrylamino)-N-pentyl-2,4,6-triiodoisophthalamate; Iopamidol Intermediate; Iohexol Intermediate; Ioversol Intermediate; 2,4,6-Triiodo-5-(N-pentylcarbamoyl)-N-butyryl-isophthalamic Acid Sodium Salt; 67292-85-7 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Butyrylamino-n-Pentyl-2,4,6-Triiodoisophthalamic Acid Sodium Salt is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and assay, residual solvent analysis, and identification by IR and NMR, to ensure it meets the exacting standards required for pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Iodine Content	Contact for details
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.