Description

5-Acetylamino-2,4,6-Triiodoisophthalamic Acid is a specialized, high-purity iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its value lies in its precise molecular structure, which is critical for developing safe and effective diagnostic imaging agents. This product is essential for pharmaceutical manufacturers and advanced research institutions focused on diagnostic chemistry and radiopharmaceutical development.

Application

• Primary Intermediate for X-ray Contrast Media: A crucial building block in the synthesis of non-ionic, low-osmolar contrast agents used in computed tomography (CT) and angiography.
• Pharmaceutical Research & Development: Serves as a key starting material for developing novel iodinated compounds with enhanced safety and imaging profiles.
• Diagnostic Agent Synthesis: Used in the manufacture of advanced diagnostic chemicals for medical imaging procedures.
• Chemical Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Specialty Organic Synthesis: Utilized in research for constructing complex molecules containing iodine for various applications.

Basic Information

Product Name	5-Acetylamino-2,4,6-Triiodoisophthalamic Acid
CAS No.	67292-83-5
Molecular Formula	C11H8I3N2O4
Molecular Weight	645.91 g/mol
Synonyms	5-Acetamido-2,4,6-triiodoisophthalamic Acid; 2,4,6-Triiodo-5-acetamido-isophthalamic Acid; 5-(Acetylamino)-2,4,6-triiodo-1,3-benzenedicarboxylic Acid; N-[2,4,6-Triiodo-3,5-bis(carboxy)phenyl]acetamide; Iohexol Intermediate; Ioversol Intermediate; Iopamidol Intermediate; Triiodoisophthalamic Acid Derivative
EINECS	Contact for details

Quality Control

Our 5-Acetylamino-2,4,6-Triiodoisophthalamic Acid is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all critical quality attributes. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider maintaining the product under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.