Description

5-Acetylamino-N,n-Dimethyl-2,4,6-Triiodoisophthalamic Acid Sodium Salt is a high-purity, iodinated organic compound primarily used as a key intermediate in the synthesis of advanced X-ray contrast media. This compound is critical for ensuring the quality and efficacy of final pharmaceutical formulations, offering reliable performance in complex chemical syntheses. It is essential for manufacturers and R&D laboratories in the pharmaceutical and diagnostic imaging industries who require a consistent and high-quality building block for contrast agent production.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of non-ionic, low-osmolar X-ray contrast agents such as Iopamidol and Ioversol.
• Contrast Media Research & Development: Serves as a fundamental building block for developing and testing new generations of iodinated contrast media with improved safety profiles.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled production of final contrast agent APIs, where purity and structural integrity are paramount.
• Diagnostic Imaging Agent Synthesis: Integral to creating compounds used in computed tomography (CT) scans, angiography, and other radiographic procedures.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control in contrast media production.
• Specialty Chemical Synthesis: Employed in organic synthesis research to create novel iodinated aromatic compounds for various biomedical applications.

Basic Information

Product Name	5-Acetylamino-N,n-Dimethyl-2,4,6-Triiodoisophthalamic Acid Sodium Salt
CAS No.	67292-81-3
Molecular Formula	C13H12I3N3NaO4
Molecular Weight	719.95 g/mol
Synonyms	5-Acetamido-N,N-dimethyl-2,4,6-triiodoisophthalamic acid sodium salt; Sodium 5-acetylamino-N,N-dimethyl-2,4,6-triiodoisophthalamate; Iopamidol Intermediate; Ioversol Intermediate; 2,4,6-Triiodo-5-[(methylamino)carbonyl]-N,N-dimethylisophthalamic acid sodium salt; 5-(Acetylamino)-N,N-dimethyl-2,4,6-triiodo-1,3-benzenedicarboxamide sodium salt; Sodium 5-acetamido-2,4,6-triiodo-N,N-dimethylisophthalamate
EINECS	Contact for details

Quality Control

Our 5-Acetylamino-N,n-Dimethyl-2,4,6-Triiodoisophthalamic Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or pharmacopeial requirements (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.