Description

n-Chloroacetyl-Dl-2-Amino-n-Butyric Acid is a specialized chiral amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which allows for selective peptide coupling and the introduction of the chloroacetyl group for further chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel peptide-based therapeutics, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Bioconjugation: The chloroacetyl group enables site-specific labeling and conjugation of peptides to other molecules, such as fluorophores or drug carriers.
• Protease Inhibitor Development: Serves as a core structure for designing and screening potential enzyme inhibitors.
• Chemical Biology Research: Employed in studies exploring protein-protein interactions and signal transduction pathways.
• Agrochemical Synthesis: Can be utilized in the research and development of novel, peptide-inspired crop protection agents.

Basic Information

Product Name	n-Chloroacetyl-Dl-2-Amino-n-Butyric Acid
CAS No.	67183-18-0
Molecular Formula	C₆H₁₀ClNO₃
Molecular Weight	179.60 g/mol
Synonyms	DL-2-Amino-2-ethylchloroacetic acid; 2-Aminobutanoic acid, N-chloroacetyl-; N-Chloroacetyl-DL-2-aminobutyric acid; Chloroacetyl-DL-2-aminobutyric acid; (RS)-2-(Chloroacetamido)butanoic acid; DL-2-(Chloroacetamido)butyric acid; 2-Aminobutyric acid, N-chloroacetyl-
EINECS	Contact for details

Quality Control

Our n-Chloroacetyl-Dl-2-Amino-n-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (DL Ratio)	~50:50 (Racemic mixture)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.