Description

Hemoglobin Coventry CAS NO 67167-49-1 is a specific, naturally occurring variant of hemoglobin, the vital oxygen-transporting protein in red blood cells. This compound is of significant interest in biochemical research and diagnostic development for studying hemoglobinopathies and related blood disorders. It serves as a critical reference standard and raw material for manufacturers and researchers in the pharmaceutical, biotechnology, and clinical diagnostics sectors, enabling advanced studies in hematology and therapeutic development.

Application

• Biochemical Research Standard: Used as a purified reference material for studying the structure, function, and stability of hemoglobin variants.
• Diagnostic Kit Development: A key component in the calibration and validation of diagnostic assays and kits for detecting hemoglobin disorders.
• Pharmaceutical Research: Employed in preclinical studies investigating potential therapies for sickle cell disease and other hemoglobinopathies.
• Clinical Laboratory Control: Serves as a quality control material in clinical laboratories to ensure accuracy in hemoglobin electrophoresis and chromatography tests.
• Academic & Educational Use: Provides a tangible model for teaching advanced concepts in protein chemistry, genetics, and molecular biology.
• Biotechnology Reagent: Utilized in the development of biosensors and other biotechnological applications that require specific protein interactions.

Basic Information

Product Name	Hemoglobin Coventry
CAS No.	67167-49-1
Molecular Formula	C2952H4664N812O840S16Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb Coventry; Hemoglobin variant Coventry; α-2 β-2(141(H19)Leu->0) Hemoglobin; Unstable Hemoglobin Coventry; HBB:c.427T>A Hemoglobin; Hemoglobin α-2 β-2(141) deletion; Deoxyhemoglobin Coventry (Ferrous); Oxyhemoglobin Coventry (Ferric)
EINECS	Contact for details

Quality Control

Our Hemoglobin Coventry is produced and handled under strict quality protocols to ensure batch-to-batch consistency and purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, electrophoresis, and spectrophotometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. Avoid repeated freeze-thaw cycles. Store in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (Electrophoresis)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	< 5%
Solubility	Clear solution in buffer
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.