Description

Chloroac-Asp-Oh CAS NO 67036-33-3 is a high-purity, protected amino acid derivative, specifically the chloroacetyl-protected form of aspartic acid. This compound is a critical building block in the synthesis of complex peptides and active pharmaceutical ingredients (APIs), offering precise control over molecular structure. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Peptide Synthesis: A key protected intermediate in solid-phase and solution-phase peptide synthesis, particularly for incorporating aspartic acid residues.
• Pharmaceutical Intermediates: Used in the research and production of therapeutic peptides and small molecule drugs.
• Bioconjugation: Serves as a versatile linker or spacer molecule for attaching functional groups to proteins or other biomolecules.
• Chemical Biology Research: A valuable tool for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical entity production.
• Protecting Group Chemistry: Utilized in multi-step organic syntheses where selective deprotection of functional groups is required.

Basic Information

Item	Details
Product Name	Chloroac-Asp-Oh
CAS No.	67036-33-3
Molecular Formula	C6H8ClNO5
Molecular Weight	209.59 g/mol
Synonyms	N-Chloroacetyl-L-aspartic Acid; (2S)-2-(2-Chloroacetamido)butanedioic Acid; L-Aspartic Acid, N-(chloroacetyl)-; Chloroacetyl-L-aspartic Acid; Chloroacetyl-DL-aspartic Acid; Aspartic Acid Chloroacetyl Derivative; N-CA-Asp-OH
EINECS	Contact for details

Quality Control

Our Chloroac-Asp-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent testing. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.