Description

6β-Hydroxy Androstenedione-D6 is a high-purity, deuterium-labeled internal standard critical for advanced analytical applications. This compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses in complex biological matrices. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and forensic toxicology labs for method development and validation in steroid metabolism studies.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the precise quantification of 6β-hydroxyandrostenedione and related steroid metabolites in pharmacokinetic and bioanalytical studies.
• Drug Metabolism Research: Facilitates the investigation of cytochrome P450 (CYP) enzyme activity, specifically CYP3A4, which is responsible for the 6β-hydroxylation pathway of steroid hormones and numerous drugs.
• Clinical Diagnostics: Supports the development of sensitive assays for measuring endogenous steroid profiles in serum, plasma, or urine, aiding in endocrine disorder diagnosis.
• Doping Control Analysis: Employed in anti-doping laboratories for the definitive identification and quantification of anabolic steroids and their metabolites in athlete samples.
• Biomarker Discovery: Enables accurate tracking of specific steroidogenic pathways in research focused on cancer, adrenal disorders, and other metabolic conditions.
• Pharmaceutical Quality Control: Serves as a reference standard in the quality assurance and stability testing of steroid-based pharmaceutical products.

Basic Information

Product Name	6β-Hydroxy Androstenedione-D6
CAS No.	67034-98-4
Molecular Formula	C19H20D6O3
Molecular Weight	304.44 g/mol
Synonyms	6β-Hydroxyandrost-4-ene-3,17-dione-d6; Androst-4-ene-3,17-dione, 6β-hydroxy-, (6β)-, labeled with deuterium; 6β-Hydroxyandrostenedione-d6; 6β-Hydroxy-4-androstene-3,17-dione-d6; 6β-Hydroxy-δ4-androstenedione-d6; 6β-OH-AD-d6; Deuterated 6β-Hydroxyandrostenedione
EINECS	Contact for details

Quality Control

Every batch of 6β-Hydroxy Androstenedione-D6 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for identity, purity (HPLC), isotopic enrichment, and specific tests.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.