Description

3,5-Bis(Butyrylamino)-2,4,6-Triiodobenzoic Acid is a high-purity, iodinated organic compound primarily used as a key intermediate in the synthesis of advanced X-ray contrast media. Its molecular structure, featuring three iodine atoms, is critical for imparting the necessary radiopacity required in diagnostic imaging agents. This compound is essential for pharmaceutical manufacturers and research institutions developing next-generation non-ionic, low-osmolar contrast agents to improve patient safety and diagnostic clarity.

Application

• Primary Intermediate for X-ray Contrast Media: Serves as the foundational building block in the synthesis of iopamidol, iopromide, and other non-ionic contrast agents.
• Pharmaceutical Research & Development: Used in the discovery and process development of new iodinated diagnostic compounds for computed tomography (CT) and angiography.
• Active Pharmaceutical Ingredient (API) Manufacturing: A critical raw material in the controlled, multi-step synthesis of final contrast agent APIs under GMP conditions.
• Chemical Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and quality control in contrast agent production.
• Radiology Adjuvant Development: Investigated for use in creating novel formulations aimed at enhancing imaging resolution and reducing side effects.

Basic Information

Product Name	3,5-Bis(Butyrylamino)-2,4,6-Triiodobenzoic Acid
CAS No.	67032-30-8
Molecular Formula	C15H17I3N2O4
Molecular Weight	677.92 g/mol
Synonyms	2,4,6-Triiodo-3,5-bis(butyrylamino)benzoic Acid; Benzoic acid, 3,5-bis(butyrylamino)-2,4,6-triiodo-; Iopamidol Intermediate; Iopromide Intermediate; Non-Ionic Contrast Agent Intermediate; 3,5-Dibutyrylamino-2,4,6-triiodobenzoic Acid; BBTBA
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Butyrylamino)-2,4,6-Triiodobenzoic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with ICH guidelines, and we support audits for cGMP compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.