Description

3,5-Diamino-2,4,6-Triiodobenzoic Acid Sodium Salt is a high-purity, iodinated aromatic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its value lies in its unique molecular structure, which provides the iodine atoms necessary for effective radiopacity in diagnostic imaging agents. This product is essential for manufacturers in the pharmaceutical and fine chemical industries, particularly those developing non-ionic, low-osmolar contrast agents for enhanced patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of iodinated X-ray contrast agents such as iopamidol, iohexol, and ioversol.
• Diagnostic Imaging: Serves as the core iodinated moiety in non-ionic, low-osmolar contrast media used in computed tomography (CT), angiography, and urography.
• Fine Chemical Synthesis: Used in research and development for creating novel triiodobenzene derivatives with potential diagnostic or therapeutic applications.
• Radiology Research: Employed in academic and industrial labs to study structure-activity relationships and develop next-generation imaging compounds.
• Contrast Media Production: Integral to GMP-scale manufacturing processes for final drug substances, ensuring high batch-to-batch consistency.

Basic Information

Product Name	3,5-Diamino-2,4,6-Triiodobenzoic Acid Sodium Salt
CAS No.	67032-28-4
Molecular Formula	C7H3I3N2NaO2
Molecular Weight	562.82 g/mol
Synonyms	Sodium 3,5-Diamino-2,4,6-Triiodobenzoate; Benzoic acid, 3,5-diamino-2,4,6-triiodo-, sodium salt; 2,4,6-Triiodo-3,5-diaminobenzoic acid sodium salt; Sodium 2,4,6-Triiodo-5-aminoisophthalate; Iopamidol Intermediate; Iohexol Intermediate; DTBA Sodium Salt; 3,5-Diamino-2,4,6-triiodohippuric acid sodium salt (related compound)
EINECS	Contact for details

Quality Control

Our 3,5-Diamino-2,4,6-Triiodobenzoic Acid Sodium Salt is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, residual solvent analysis, and heavy metals screening, to ensure compliance with ICH guidelines and customer-specific requirements. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.