Description

Chlornaltrexamine is a potent and selective opioid receptor antagonist of significant interest in pharmacological research. This compound is a key tool for studying opioid receptor function, mechanisms of action, and potential therapeutic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and chemical suppliers serving the life sciences sector for advanced neuropharmacological investigations.

Application

• Pharmacological Research: A critical reference standard and tool compound for in vitro and in vivo studies of opioid receptor antagonism.
• Neuroscience Studies: Used to investigate pain pathways, addiction mechanisms, and the neurobiological effects of opioid modulation.
• Drug Discovery & Development: Serves as a lead compound or molecular scaffold for designing new therapeutic agents targeting opioid receptors.
• Biochemical Assays: Employed in receptor binding assays and functional studies to characterize new chemical entities.
• Academic Research: Essential for university and institutional labs conducting fundamental research in neurochemistry and behavioral pharmacology.
• Reference Standard: Used for analytical method development, validation, and quality control in laboratories synthesizing or handling related compounds.

Basic Information

Product Name	Chlornaltrexamine
CAS No.	67025-94-9
Molecular Formula	C23H30ClN3O3
Molecular Weight	431.96 g/mol
Synonyms	CNA; Chlornaltrexamine dihydrochloride; 17-(Cyclopropylmethyl)-4,5α-epoxy-6-chloro-3,14-dihydroxymorphinan-6-one; 6β-Chlornaltrexamine; 6-Chlornaltrexamine; (5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-6-chloro-3,14-dihydroxymorphinan-6-one; β-Chlornaltrexamine
EINECS	Contact for details

Quality Control

Our Chlornaltrexamine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.