Description

3-Acetylamino-2,4,6-Triiodo-5-Valerylaminobenzoic Acid is a high-purity, iodinated benzoic acid derivative with significant utility in advanced chemical synthesis. This compound matters as a critical intermediate for producing specialized X-ray contrast media and other diagnostic imaging agents, where its precise structure is essential for efficacy and safety. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and production organizations (CDMOs) focused on diagnostic and contrast agent development.

Application

• Key Intermediate for X-ray Contrast Media: Serves as a crucial building block in the synthesis of non-ionic, triiodinated contrast agents used in medical imaging procedures such as angiography, urography, and computed tomography (CT) scans.
• Pharmaceutical Research & Development: Used in the discovery and development of novel diagnostic compounds, leveraging its high iodine content for radiopacity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex, iodinated aromatic molecules for specialized applications.
• Contract Manufacturing: Supplied to CDMOs and API manufacturers producing commercial-scale batches of contrast agents under GMP guidelines.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control in contrast agent production.

Basic Information

Product Name	3-Acetylamino-2,4,6-Triiodo-5-Valerylaminobenzoic Acid
CAS No.	67011-44-3
Molecular Formula	C14H15I3N2O4
Molecular Weight	671.99 g/mol
Synonyms	5-(N-Valerylamino)-3-acetamido-2,4,6-triiodobenzoic Acid; 3-Acetamido-2,4,6-triiodo-5-valeramidobenzoic Acid; 3-Acetylamino-5-valeryl amino-2,4,6-triiodobenzoic Acid; 2,4,6-Triiodo-3-acetylamino-5-valerylaminobenzoic Acid; Benzoic acid, 3-(acetylamino)-2,4,6-triiodo-5-[(1-oxopentyl)amino]-; Iopentol Intermediate; Ioversol Related Compound; Contrast Agent Intermediate B
EINECS	Contact for details

Quality Control

Our 3-Acetylamino-2,4,6-Triiodo-5-Valerylaminobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support development and production aligned with ICH guidelines and can supply material suitable for use under GMP conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.