Description

6-Bromo-1-Hexyne is a versatile alkyne building block with a terminal bromine functional group, enabling a wide range of organic synthesis reactions. Its bifunctional nature makes it a critical intermediate for constructing complex molecular architectures in advanced research and industrial applications. This compound is particularly valuable for pharmaceutical chemists, agrochemical researchers, and material scientists developing novel polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in cross-coupling reactions like Sonogashira coupling.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific alkyne linkages.
• Material Science: Serves as a monomer or precursor for functional polymers, dendrimers, and liquid crystalline materials with tailored properties.
• Organic Synthesis & Research: A fundamental reagent for constructing carbon-carbon bonds, introducing hexynyl groups, and creating complex organic molecules in academic and industrial R&D laboratories.
• Chemical Biology: Utilized in bioconjugation and probe development for labeling biomolecules due to its reactive alkyne handle for click chemistry.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, fragrances, and advanced electronic materials.

Basic Information

Product Name	6-Bromo-1-Hexyne
CAS No.	66977-99-9
Molecular Formula	C6H9Br
Molecular Weight	161.04 g/mol
Synonyms	1-Bromo-5-hexyne; 5-Hexyn-1-yl bromide; Bromohex-1-yne; 6-Bromohex-1-yne; 1-Hexyne, 6-bromo-; 5-Hexynyl bromide
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Hexyne is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.