Description

Boc-Cys(Et)-Oh.Dcha is a protected cysteine derivative, specifically the tert-butoxycarbonyl (Boc) protected form of S-ethyl cysteine, isolated as its dicyclohexylamine (Dcha) salt. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), where it provides a stable, orthogonal protecting group strategy for the thiol functionality, preventing unwanted side reactions during chain assembly. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Peptide Synthesis: A key intermediate for the controlled incorporation of S-ethyl cysteine into peptide sequences, enabling the study of structure-activity relationships.
• Pharmaceutical Research: Used in the R&D of novel peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation Chemistry: Serves as a precursor for introducing thiol-reactive handles or stable thioether linkages into biomolecules.
• Chemical Biology: Employed in the synthesis of labeled peptides and activity-based probes for studying protein function and interaction.
• Material Science: Potential use in creating functionalized surfaces or polymers via thiol-ene or other thiol-based coupling reactions.

Basic Information

Product Name	Boc-Cys(Et)-Oh.Dcha
CAS No.	66960-13-2
Molecular Formula	C₁₈H₃₄N₂O₄S
Molecular Weight	374.54 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-S-ethyl-L-cysteine Dicyclohexylamine Salt; Boc-S-ethyl-L-cysteine DCHA salt; Boc-Cys(Et)-OH·DCHA; (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(ethylsulfanyl)propanoic acid - N-cyclohexylcyclohexanamine (1:1); N-α-Boc-S-ethyl-L-cysteine Dicyclohexylammonium Salt; Boc-L-Cys(Et)-OH·DCHA; BOC-CYS(ET)-OH DCHA SALT; tert-Butyloxycarbonyl-S-ethylcysteine Dicyclohexylamine Salt
EINECS	Contact for details

Quality Control

Our Boc-Cys(Et)-Oh.Dcha is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.