Description

Glycine, n-(n-Methylglycyl)-, Methyl Ester, Monohydrochloride is a specialized, high-purity peptide derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a protected amino acid derivative, enabling precise chemical modifications in complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in peptide synthesis, medicinal chemistry, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: Serves as a key intermediate or protected amino acid building block in solid-phase and solution-phase peptide synthesis.
• Medicinal Chemistry Research: Used in the design and synthesis of novel drug candidates, particularly for exploring structure-activity relationships (SAR).
• Bioconjugation: Acts as a chemical linker or spacer in the conjugation of peptides to other molecules, such as dyes, polymers, or drug delivery systems.
• Biochemical Research: Employed in the study of enzyme substrates, inhibitors, or as a standard in analytical method development.
• Pharmaceutical Intermediates: A crucial precursor in the multi-step synthesis of complex therapeutic peptides and peptidomimetics.

Basic Information

Product Name	Glycine, n-(n-Methylglycyl)-, Methyl Ester, Monohydrochloride
CAS No.	66959-81-7
Molecular Formula	C6H13ClN2O3
Molecular Weight	196.63 g/mol
Synonyms	N-(N-Methylglycyl)glycine methyl ester hydrochloride; Methyl N-(N-methylglycyl)glycinate hydrochloride; Glycine, N-(N-methylglycyl)-, methyl ester, hydrochloride; Methyl 2-[(2-methoxy-2-oxoethyl)(methyl)amino]acetate hydrochloride; N-Methylsarcosylglycine methyl ester hydrochloride; Sarcosylglycine methyl ester hydrochloride; Peptide synthesis intermediate 66959-81-7
EINECS	Contact for details

Quality Control

Our Glycine, n-(n-Methylglycyl)-, Methyl Ester, Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.