Description

2-Bromo-4-Methoxyphenylacetonitrile is a versatile and high-purity brominated aromatic nitrile building block. This compound is valued for its reactive benzylic and cyano functional groups, which make it a critical intermediate in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted phenylacetonitrile motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the bromine and methoxy groups offer sites for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Bromo-4-Methoxyphenylacetonitrile
CAS No.	66916-98-1
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	(2-Bromo-4-methoxyphenyl)acetonitrile; 2-Bromo-4-methoxybenzyl cyanide; 4-Methoxy-2-bromobenzyl cyanide; α-Bromo-4-methoxyphenylacetonitrile; 2-Bromo-4-methoxy-α-tolunitrile; 66916-98-1; (2-Bromo-4-methoxyphenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Methoxyphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.