Description

Carbobenzyloxy-L-Alanyl-L-Valine Benzyl Ester is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex therapeutic peptides and peptidomimetics.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid derivative for the sequential assembly of peptide chains on resin.
• Biochemical Research: Employed in studies of enzyme-substrate interactions, protein folding, and structure-activity relationships (SAR).
• Antibiotic Development: Serves as a precursor in the synthesis of certain peptide-based antibiotic compounds.
• Hormone Analog Synthesis: Used in the creation of analogs for hormones and other biologically active peptides.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse peptide libraries for high-throughput screening.

Basic Information

Product Name	Carbobenzyloxy-L-Alanyl-L-Valine Benzyl Ester
CAS No.	66880-97-5
Molecular Formula	C23H28N2O5
Molecular Weight	412.48 g/mol
Synonyms	Z-Ala-Val-OBzl; Cbz-Ala-Val-OBzl; N-Carbobenzyloxy-L-alanyl-L-valine benzyl ester; Benzyl N-[(benzyloxy)carbonyl]-L-alanyl-L-valinate; Z-L-Ala-L-Val-OBzl; CBZ-L-Alanyl-L-Valine Benzyl Ester; Nα-Cbz-L-alanyl-L-valine benzyl ester; L-Valine, N-[(phenylmethoxy)carbonyl]-L-alanyl-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our Carbobenzyloxy-L-Alanyl-L-Valine Benzyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.