Description

Boc-Met-Leu-Ome is a protected tripeptide derivative, specifically N-tert-Butoxycarbonyl-Methionyl-Leucine Methyl Ester, widely used as a critical building block in peptide synthesis. Its value lies in providing a precisely controlled sequence of methionine and leucine with orthogonal protecting groups, enabling efficient and selective chain elongation. This compound is essential for researchers and manufacturers in pharmaceutical development, biochemical research, and the production of custom peptides for therapeutic and diagnostic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of methionine and leucine residues into longer peptide chains.
• Pharmaceutical Intermediates: Serves as a crucial precursor in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Used to synthesize peptide segments for labeling, imaging, or targeting applications in biochemical assays.
• Academic & Industrial Research: A fundamental reagent for studying peptide structure, function, and metabolism in laboratory settings.
• Custom Peptide Production: Employed by CROs and CDMOs for the contract manufacturing of specific peptide sequences for clients.

Basic Information

Product Name	Boc-Met-Leu-Ome
CAS No.	66880-59-9
Molecular Formula	C20H36N2O6S
Molecular Weight	432.58 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-methionyl-L-leucine Methyl Ester; Boc-L-Met-L-Leu-OMe; Boc-Met-Leu-OMe; tert-Butyloxycarbonylmethionylleucine Methyl Ester; (2S)-2-[[(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]-4-methylpentanoic Acid Methyl Ester; Boc-Methionyl-Leucine Methyl Ester; N-Boc-Methionine-Leucine Methyl Ester
EINECS	Contact for details

Quality Control

Our Boc-Met-Leu-Ome is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and identity. We adhere to cGMP guidelines where applicable to support our clients in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0% (L-L isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.