Description

11Beta-Hydroxy-D-Homopregna-1,4-Diene-3,20-Dione 17A-Butyrate is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory drug discovery. This compound is essential for R&D chemists and pharmaceutical manufacturers focused on developing next-generation steroid-based pharmaceuticals and conducting detailed structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel corticosteroid analogs and other bioactive steroid molecules.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and the exploration of new therapeutic pathways.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	11Beta-Hydroxy-D-Homopregna-1,4-Diene-3,20-Dione 17A-Butyrate
CAS No.	66877-67-6
Molecular Formula	C25H34O5
Molecular Weight	414.53 g/mol
Synonyms	11β-Hydroxy-D-homopregna-1,4-diene-3,20-dione 17α-butyrate; 11β-Hydroxy-17α-butyryloxy-D-homopregna-1,4-diene-3,20-dione; 17α-Butyryl-11β-hydroxy-D-homopregna-1,4-diene-3,20-dione; D-Homoprednisolone 17α-butyrate; 11β,17α-Dihydroxy-17α-butyryl-D-homopregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our 11Beta-Hydroxy-D-Homopregna-1,4-Diene-3,20-Dione 17A-Butyrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.