Description

Hemoglobin Louisville CAS NO 66796-10-9 is a specific, naturally occurring variant of human hemoglobin, characterized by a point mutation in the β-globin chain. This product is of significant value for biochemical research and diagnostic development, providing a precise tool for studying hemoglobinopathies and oxygen transport mechanisms. It is essential for researchers and manufacturers in the fields of hematology, clinical diagnostics, and biopharmaceutical development who require high-purity, well-characterized hemoglobin standards.

Application

• Biochemical Research Standard: Used as a reference material in studies of hemoglobin structure, function, and stability.
• Clinical Diagnostics Development: Serves as a critical component in the calibration and validation of diagnostic assays for hemoglobin variants.
• Hematology Studies: Employed in research focused on oxygen-binding affinity and the pathophysiology of related blood disorders.
• Pharmaceutical R&D: Acts as a model compound in the development of therapeutic agents targeting sickle cell disease and other hemoglobinopathies.
• Educational & Laboratory Use: Provides a specific example for advanced teaching and laboratory training in protein chemistry and molecular biology.

Basic Information

Item	Detail
Product Name	Hemoglobin Louisville
CAS No.	66796-10-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb Louisville; Hemoglobin β42 (CD1) Phe→Leu; Hemoglobin variant Louisville; β-42 Phe->Leu hemoglobin; HBB: c.127T>C; Unstable hemoglobin Louisville; Hemoglobinopathy Louisville; Oxyhemoglobin Louisville
EINECS	Contact for details

Quality Control

Our Hemoglobin Louisville is produced and handled under stringent quality protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and biological activity. Certificates of Analysis (COA) documenting purity (by HPLC), spectral identification, and physical characteristics are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR / UV-Vis)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	Contact for details
Methemoglobin Content	< 5%
Solubility	Clear solution in buffer
Biological Activity (O2 binding)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.