Description

Encainide Hydrochloride is a high-purity pharmaceutical intermediate and reference standard of significant importance in cardiovascular research and development. Its primary value lies in its role as the active pharmaceutical ingredient (API) metabolite of the Class IC antiarrhythmic agent, encainide, used in critical pharmacological studies. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly those focused on cardiology, drug metabolism, pharmacokinetics, and analytical method development. Precise synthesis and rigorous quality control ensure its suitability for advanced laboratory and scale-up applications.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control, analytical method validation, and regulatory submissions in API manufacturing.
• Cardiovascular Research: Serves as a key metabolite in preclinical and clinical studies investigating the pharmacology, efficacy, and safety profile of antiarrhythmic drugs.
• Active Pharmaceutical Ingredient (API) Intermediate: A critical building block in the synthesis and development of encainide and related therapeutic compounds.
• Metabolite Studies: Employed in drug metabolism and pharmacokinetic (DMPK) research to understand the biotransformation pathways of encainide.
• Analytical Chemistry: Utilized in laboratories for developing and calibrating HPLC, LC-MS, and other chromatographic assays for drug detection and quantification.

Basic Information

Product Name	Encainide Hydrochloride
CAS No.	66794-74-9
Molecular Formula	C22H28N2O2·HCl
Molecular Weight	388.93 g/mol
Synonyms	4-Methoxy-N-[2-[2-(1-methyl-2-piperidyl)ethyl]phenyl]benzamide hydrochloride; (±)-4-Methoxy-N-[2-[2-(1-methyl-2-piperidyl)ethyl]phenyl]benzamide hydrochloride; Encainide HCl; MJ 9067-1; ENCAINIDE HYDROCHLORIDE (USP); O-Desmethyl Encainide Hydrochloride (major metabolite); Contact for details on additional aliases.
EINECS	Contact for details

Quality Control

Our Encainide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.