Description

1,2,3-Trifluoropropane is a versatile fluorinated organic compound with the CAS number 66794-36-3, valued for its unique physicochemical properties derived from its fluorine substitution pattern. This compound serves as a critical building block and intermediate in advanced chemical synthesis, particularly in the pharmaceutical and agrochemical sectors. It is essential for manufacturers and R&D laboratories seeking to develop novel molecules with enhanced stability, bioavailability, or specific activity.

Application

• Pharmaceutical Intermediate: A key synthon in the production of active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for metabolic stability.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides where fluorine atoms improve efficacy and environmental persistence.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and coupling reactions to introduce the trifluoropropane moiety into complex organic frameworks.
• Solvent & Reaction Medium: Functions as a specialty fluorinated solvent for specific reactions requiring non-polar, thermally stable media.
• Material Science Precursor: Acts as a starting material for synthesizing fluorinated polymers, coatings, or surface modifiers.
• Refrigerant & Propellant Research: Investigated as a potential component in next-generation, low-global-warming-potential (GWP) refrigerant blends.

Basic Information

Product Name	1,2,3-Trifluoropropane
CAS No.	66794-36-3
Molecular Formula	C3H5F3
Molecular Weight	98.07 g/mol
Synonyms	1,2,3-Trifluoropropane; Trifluoropropane; Propane, 1,2,3-trifluoro-; 66794-36-3; NSC 9235; 1,2,3-Trifluoropropan; UNII-9J2K91F0A0
EINECS	Contact for details

Quality Control

Our 1,2,3-Trifluoropropane is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets precise specifications for purity and identity. A comprehensive Certificate of Analysis (COA) detailing results for assay, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 1.0% total
Density (20°C)	~1.2 g/mL
Boiling Point	~40-45°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.