Description

N,N'-Bis(Vinylsulfonylacetyl)Ethylenediamine is a specialized bifunctional crosslinking agent featuring reactive vinyl sulfone groups. This compound is valued for its ability to form stable covalent bonds with nucleophiles such as thiols and amines under mild conditions, enabling precise bioconjugation and material modification. It is essential for researchers and manufacturers in the life sciences, polymer chemistry, and advanced materials sectors seeking reliable, high-performance crosslinkers.

Application

• Bioconjugation and Protein Modification: Used to crosslink antibodies, enzymes, and other proteins with drugs, fluorescent dyes, or solid supports for diagnostics and therapeutics.
• Hydrogel Formation: Serves as a key crosslinker in the synthesis of biocompatible hydrogels for drug delivery systems and tissue engineering scaffolds.
• Polymer Functionalization: Imparts reactive sites onto polymer backbones (e.g., PEG, dextran) to create functionalized materials for further chemical grafting.
• Surface Immobilization: Facilitates the covalent attachment of biomolecules onto chips, beads, and other surfaces for biosensor and microarray development.
• Antibody-Drug Conjugate (ADC) Linker Chemistry: Acts as a linker component in the construction of stable ADCs, connecting cytotoxic payloads to targeting antibodies.
• Material Science Research: Employed in R&D for developing novel crosslinked networks with tailored mechanical and chemical properties.

Basic Information

Product Name	N,N'-Bis(Vinylsulfonylacetyl)Ethylenediamine
CAS No.	66710-66-5
Molecular Formula	C12H18N2O6S2
Molecular Weight	350.41 g/mol
Synonyms	1,2-Bis[(vinylsulfonyl)acetamido]ethane; Ethylenediamine, N,N'-bis(2-(vinylsulfonyl)acetyl)-; BVS-Acetyl-EDA; Bis(vinylsulfonylacetyl)ethylenediamine; VS-VS crosslinker; Bifunctional vinyl sulfone crosslinker; N,N'-Ethylenebis[2-(vinylsulfonyl)acetamide]
EINECS	Contact for details

Quality Control

Our N,N'-Bis(Vinylsulfonylacetyl)Ethylenediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; partially soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.