Description

Methanesulfonic Acid, Trifluoro-, 2,2-Dimethylpropyl Ester is a specialized fluorinated sulfonate ester, a high-value intermediate in advanced organic synthesis. This compound matters for its role in introducing the robust trifluoromethanesulfonyl (triflyl) group, which is critical for modifying the properties of target molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block and protecting group reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring enhanced metabolic stability or lipophilicity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Polymer & Material Science: Acts as a monomer or modifier in the production of specialty polymers, including fluorinated polymers with unique thermal, chemical, and surface properties.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Electrolyte Additive: Investigated for use as a component in advanced electrolyte formulations for lithium-ion batteries to improve performance and safety.
• Organic Synthesis Reagent: Functions as a versatile reagent for trifluoromethanesulfonylation (triflation) reactions, converting alcohols into excellent leaving groups for nucleophilic substitution.

Basic Information

Product Name	Methanesulfonic Acid, Trifluoro-, 2,2-Dimethylpropyl Ester
CAS No.	66687-89-6
Molecular Formula	C7H11F3O3S
Molecular Weight	232.22 g/mol
Synonyms	Neopentyl Trifluoromethanesulfonate; 2,2-Dimethylpropyl Triflate; Pivalyl Triflate; 2,2-Dimethyl-1-propanol Trifluoromethanesulfonate; 1,1-Dimethylethylmethyl Triflate; Trifluoromethanesulfonic Acid Neopentyl Ester; Neopentyl Triflate; (2,2-Dimethylpropoxy)sulfonyl Trifluoride
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid, Trifluoro-, 2,2-Dimethylpropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific data are provided to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its nature as an organic solvent ester, ensure containers are kept tightly sealed when not in use to prevent moisture ingress and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.