Description

2,3-Difluoro-6-Nitroanisole is a fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro substituents, which are crucial for modulating the electronic and steric properties of target molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro-nitroanisole structure contributes to biological activity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and electronic materials that benefit from fluorinated aromatic units.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and reduction reactions to create diverse chemical libraries.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and colorants.

Basic Information

Product Name	2,3-Difluoro-6-Nitroanisole
CAS No.	66684-65-9
Molecular Formula	C7H5F2NO3
Molecular Weight	189.12 g/mol
Synonyms	1,2-Difluoro-3-methoxy-4-nitrobenzene; 2,3-Difluoro-6-nitroanisole; 3-Methoxy-2,3-difluoronitrobenzene; 2,3-Difluoro-1-methoxy-4-nitrobenzene; Benzene, 1,2-difluoro-3-methoxy-4-nitro-; 6-Nitro-2,3-difluoroanisole
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Nitroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.