Description

Cbz-L-Alaninol CAS NO 66674-16-6 is a high-purity, protected amino alcohol derivative widely used as a critical chiral building block in organic synthesis. This compound is essential for constructing complex molecular architectures, particularly in the pharmaceutical and bioconjugation sectors, due to its reactive amine and alcohol functionalities. It is primarily utilized by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development of peptide mimetics, active pharmaceutical ingredients (APIs), and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other small molecule therapeutics.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce the L-alaninol moiety into peptide chains, modifying their properties.
• Linker and Spacer Unit: Employed in bioconjugation and the development of antibody-drug conjugates (ADCs) and prodrugs.
• Asymmetric Synthesis: Serves as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions.
• Material Science: A monomer or precursor for functional polymers and dendrimers with specific chemical handles.
• Chemical Biology Research: Utilized in the synthesis of molecular probes and tools for studying biological processes.

Basic Information

Product Name	Cbz-L-Alaninol
CAS No.	66674-16-6
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	N-Carbobenzoxy-L-alaninol; (S)-2-(((Benzyloxy)carbonyl)amino)propan-1-ol; (S)-N-Cbz-2-Aminopropanol; (S)-N-Cbz-Alaninol; Nα-Cbz-L-alaninol; Z-L-Alaninol; (S)-1-Hydroxy-2-[(phenylmethoxy)carbonylamino]propane; L-Alaninol, N-[(phenylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Cbz-L-Alaninol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.