Description

3,3'-Difluorobenzoin is a high-purity fluorinated organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its role as a key building block for constructing complex molecules, particularly in the development of pharmaceuticals and specialty materials. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate difluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a difluorobenzil or difluorostilbene core structure.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds used in display technologies.
• Polymer Chemistry: Employed in the creation of specialty polymers with tailored thermal, optical, or surface properties.
• Cross-Coupling Reactions: Acts as a substrate or ligand precursor in palladium-catalyzed cross-coupling reactions for complex molecule assembly.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory synthesis in organic and medicinal chemistry laboratories.

Basic Information

Product Name	3,3'-Difluorobenzoin
CAS No.	66659-65-2
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	3,3'-Difluorobenzoin; 1,2-Bis(3-fluorophenyl)-2-hydroxyethanone; α-Hydroxy-3,3'-difluorobenzyl Phenyl Ketone; 2-Hydroxy-1,2-bis(3-fluorophenyl)ethanone; 3-Fluorobenzoin; Bis(3-fluorophenyl)(hydroxy)ethanone
EINECS	Contact for details

Quality Control

Our 3,3'-Difluorobenzoin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed batch-specific data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.