Description

Dfmo CAS NO 66640-93-5 is a high-purity, non-proteinogenic amino acid analog with significant biochemical activity. This compound is a critical intermediate and active ingredient in advanced pharmaceutical research and development, valued for its specific inhibitory properties. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for applications in oncology, parasitology, and metabolic studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of investigational drugs and therapeutic agents.
• Oncology Research: Used in preclinical and clinical research as an ornithine decarboxylase (ODC) inhibitor for studying cancer cell proliferation and developing targeted therapies.
• Antiparasitic Agent: Employed in research for the treatment of African sleeping sickness (Trypanosoma brucei infection) and other parasitic diseases.
• Biochemical Research: Acts as a specific tool compound in polyamine biosynthesis pathway studies and cellular metabolism research.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Cosmetic & Dermatology R&D: Investigated for potential applications in topical formulations targeting unwanted hair growth.

Basic Information

Product Name	Dfmo
CAS No.	66640-93-5
Molecular Formula	C6H12F2N2O2
Molecular Weight	182.17 g/mol
Synonyms	Eflornithine; 2-(Difluoromethyl)ornithine; DFMO; α-Difluoromethylornithine; Ornidyl; DMFO; (RS)-2-(Difluoromethyl)ornithine; DL-α-Difluoromethylornithine
EINECS	Contact for details

Quality Control

Our Dfmo is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.