Description

1H-Thieno[3,4-D)Imidazole-4-Pentanamide, N, n-Bis[2-(Diphenylphosphino )Ethyl]Hexahydro-2-Oxo-, (3A.Alpha., 4.Beta.,6A.Alpha.)- CAS NO 66561-97-5 is a specialized organophosphorus compound featuring a complex heterocyclic structure. This chemical is valued for its role as a highly effective ligand and catalyst precursor in advanced synthetic chemistry, particularly in asymmetric transformations. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active ingredients and complex intermediates.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including hydrogenation and cross-coupling.
• Pharmaceutical Intermediate: Key building block in the synthesis of complex, stereochemically defined drug candidates.
• Fine Chemical Synthesis: Enabling the production of high-value, optically pure compounds for agrochemicals and specialty materials.
• Academic & Industrial Research: A valuable tool for methodological development in organic and organometallic chemistry.
• Ligand Library Development: Component in screening libraries for discovering new catalytic systems.

Basic Information

Item	Details
Product Name	1H-Thieno[3,4-D)Imidazole-4-Pentanamide, N, n-Bis[2-(Diphenylphosphino )Ethyl]Hexahydro-2-Oxo-, (3A.Alpha., 4.Beta.,6A.Alpha.)-
CAS No.	66561-97-5
Molecular Formula	C39H42N3O2P2S
Molecular Weight	678.79 g/mol
Synonyms	N,N-Bis[2-(diphenylphosphino)ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-, (3aα,4β,6aα)-; (3aα,4β,6aα)-N,N-Bis[2-(diphenylphosphino)ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; Chiral Thienoimidazole Phosphine Ligand; Asymmetric Diphosphine Ligand; Catalyst Precursor 66561-97-5.
EINECS	Contact for details

Quality Control

Our production of this advanced ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and chiral analysis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.