Description

2,5-Piperazinedione,1,3-Dimethyl-,(R)-(9Ci) is a chiral piperazinedione derivative, a key structural motif and advanced intermediate in organic synthesis. This compound matters for its role as a versatile building block in the development of complex, biologically active molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development and study of new asymmetric catalytic reactions.
• Peptidomimetic Chemistry: Serves as a constrained dipeptide analog for constructing peptidomimetics with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: An intermediate in the research and development of advanced, chiral active ingredients for crop protection.
• Academic & Institutional R&D: Employed in university and research institute laboratories for fundamental studies in heterocyclic and stereoselective chemistry.
• Custom Synthesis & Contract Manufacturing: A specified starting material for custom synthesis projects requiring high-purity, enantiomerically enriched intermediates.

Basic Information

Product Name	2,5-Piperazinedione,1,3-Dimethyl-,(R)-(9Ci)
CAS No.	66445-41-8
Molecular Formula	C6H10N2O2
Molecular Weight	142.16 g/mol
Synonyms	(R)-1,3-Dimethylpiperazine-2,5-dione; (R)-1,3-Dimethyl-2,5-piperazinedione; (R)-1,3-Dimethyl-2,5-diketopiperazine; (R)-DMDKP; (R)-1,3-Dimethyl-2,5-dioxopiperazine; (R)-1,3-Dimethylpiperazine-2,5-diketone; (R)-1,3-Dimethyl-2,5-piperazinedione (9CI); (R)-1,3-Dimethyl-2,5-dioxo-piperazine
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,1,3-Dimethyl-,(R)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.