Description

tert-Butyl 4-Cyanobenzylcarbamate is a high-purity, protected amino acid derivative widely used as a critical building block in organic synthesis. Its value lies in its dual functionality, where the carbamate group provides a protected amine for peptide coupling, and the cyano group offers a versatile handle for further chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and oncology.
• Peptide Synthesis: Serves as a protected amino acid building block (Boc-protected) for solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the reactivity of the cyano group.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for biochemical research and diagnostic applications.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific chiral or functionalized intermediates.

Basic Information

Product Name	tert-Butyl 4-Cyanobenzylcarbamate
CAS No.	66389-80-8
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	Boc-4-Cyanobenzylamine; N-(tert-Butoxycarbonyl)-4-cyanobenzylamine; 4-Cyanobenzylcarbamic acid tert-butyl ester; 1-[(tert-Butoxycarbonyl)amino]methyl]-4-cyanobenzene; tert-Butyl N-[(4-cyanophenyl)methyl]carbamate; Boc-4-Cyanobenzylamine; N-Boc-4-cyanobenzylamine; 4-Cyano-Boc-benzylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyanobenzylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.