Description

Paclobutrazol Impurity 2 is a specified impurity and reference standard used in the analytical profiling of the plant growth regulator Paclobutrazol. This compound is critical for ensuring the purity, safety, and regulatory compliance of Paclobutrazol-based agrochemical formulations. It is primarily required by quality control laboratories, research institutions, and manufacturers in the agrochemical and pharmaceutical industries for method development, validation, and routine batch analysis.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of Paclobutrazol Impurity 2 in active pharmaceutical ingredients (APIs) and technical-grade materials.
• Method Development & Validation: Essential for developing and validating chromatographic methods (HPLC, GC) to monitor impurities in Paclobutrazol synthesis and formulation processes.
• Quality Control & Assurance: Serves as a critical tool in QC laboratories to establish specification limits and ensure batch-to-batch consistency and compliance with ICH guidelines.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., for EPA, FDA) by providing definitive proof of impurity characterization and control strategies.
• Research & Development: Used in stability studies and degradation pathway analysis to understand the formation and behavior of this specific impurity.
• Chemical Synthesis Monitoring: Employed to optimize synthesis routes by tracking the formation and reduction of this impurity during production.

Basic Information

Item	Detail
Product Name	Paclobutrazol Impurity 2
CAS No.	66345-53-7
Molecular Formula	C15H20ClN3O
Molecular Weight	293.79 g/mol
Synonyms	(2RS,3RS)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol; Paclobutrazol Related Compound B; (2RS,3RS)-Paclobutrazol Impurity; UNII-7B2F4S2L5I; 1-(4-Chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol; Potential Paclobutrazol Metabolite; Paclobutrazol Isomer
EINECS	Contact for details

Quality Control

Every batch of Paclobutrazol Impurity 2 is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC, GC, and NMR to ensure they meet the high standards required for reference materials. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific results and confirming compliance with in-house specifications aligned with ICH Q3A/B guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 1.0% Total impurities: ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.