Description

4-Methylumbelliferyl Decanoate is a synthetic fluorogenic substrate and a key biochemical reagent. This compound is valued for its role as a chromogenic and fluorogenic probe in enzymatic assays, particularly for detecting lipase and esterase activity. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries who require precise, sensitive tools for enzyme kinetics and inhibitor screening studies. CAS No. 66185-70-4.

Application

• Enzymatic Assay Substrate: Primary fluorogenic substrate for the detection and quantification of lipase and esterase enzyme activity.
• Biochemical Research: Used in kinetic studies, high-throughput screening (HTS) for enzyme inhibitors, and mechanistic studies of ester hydrolysis.
• Diagnostic Reagent Manufacturing: A critical component in the formulation of diagnostic kits for clinical and veterinary analysis of pancreatic function and lipid metabolism disorders.
• Pharmaceutical Development: Employed in drug discovery pipelines to screen for potential therapeutic agents targeting lipolytic enzymes.
• Microbiology & Cell Biology: Used as a stain to visualize esterase activity within cells and tissues, and to study microbial lipase production.
• Food & Industrial Enzyme Analysis: Applied in quality control to measure lipase activity in enzyme preparations used in food processing, detergents, and biofuels.

Basic Information

Product Name	4-Methylumbelliferyl Decanoate
CAS No.	66185-70-4
Molecular Formula	C₂₀H₂₆O₅
Molecular Weight	346.42 g/mol
Synonyms	4-MU Decanoate; 4-Methylumbelliferyl Caprate; 4-Methyl-7-hydroxycoumarin decanoate; Decanoic acid 4-methyl-2-oxo-2H-chromen-7-yl ester; 7-Hydroxy-4-methylcoumarin decanoate; 4-Methylumbelliferone decanoate; Lipase substrate 4-MU decanoate; Fluorogenic lipase substrate
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl Decanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and verification of fluorogenic performance. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, assay value, and physical properties, ensuring consistency and reliability for your critical research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Fluorogenic Activity	Functional test passed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.