Description

1-Methyl-1H-Imidazole-4-Carbonitrile is a versatile heterocyclic building block and key synthetic intermediate prized for its reactive nitrile and imidazole functionalities. This compound is essential for the development of advanced pharmaceuticals, agrochemicals, and specialty materials, offering a critical scaffold for molecular diversification. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules, including potential active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting central nervous system disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of ionic liquids, conductive polymers, and other advanced functional materials due to the imidazole moiety.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis organizations (CSOs) and CDMOs serving the life sciences sector.

Basic Information

Product Name	1-Methyl-1H-Imidazole-4-Carbonitrile
CAS No.	66121-69-5
Molecular Formula	C5H5N3
Molecular Weight	107.11 g/mol
Synonyms	1-Methyl-1H-imidazole-4-carbonitrile; 4-Cyano-1-methylimidazole; 1-Methyl-4-cyanoimidazole; 1-Methylimidazole-4-carbonitrile; 4-CN-1-MeIm; 66121-69-5; 1-Methyl-4-imidazolecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Imidazole-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.