Description

Iohexol is a non-ionic, water-soluble, iodinated contrast medium widely used in radiographic imaging procedures. Its primary value lies in its excellent safety profile and high radiopacity, which enables clear visualization of blood vessels, organs, and body cavities. This product is essential for manufacturers in the pharmaceutical and diagnostic industries, particularly for formulating injectable solutions used in angiography, myelography, urography, and computed tomography (CT) scans.

Application

• X-ray Contrast Media: Primary component in injectable formulations for intravascular administration.
• Angiography: Used for imaging of coronary, cerebral, and peripheral arteries.
• Urography/Excretory Urography: For radiographic examination of the kidneys, ureters, and bladder.
• Myelography: Contrast agent for imaging the spinal cord and subarachnoid space.
• Computed Tomography (CT): Enhances contrast in body and head CT scans.
• Arthrography: Used for imaging joint spaces.
• Pharmaceutical Intermediate: Serves as a key raw material in the synthesis of finished dosage forms.
• Research & Development: Utilized in biochemical and medical research involving imaging techniques.

Basic Information

Product Name	Iohexol
CAS No.	66108-95-0
Molecular Formula	C19H26I3N3O9
Molecular Weight	821.14 g/mol
Synonyms	5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide; Omnipaque (Trade Name); Iopamidol analog; Nycodenz; Iohexolum; WIN 39424; Non-ionic contrast medium; Triiodinated isophthalamide derivative
EINECS	266-074-4

Quality Control

Our Iohexol is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes rigorous analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical active ingredients. A comprehensive Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Iodine Content	46.0% - 46.8%
pH (5% Solution)	6.5 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.