Description

2-(4-Ethynylphenyl)Propan-2-Ol is a high-purity organic building block characterized by its terminal alkyne and tertiary alcohol functional groups. This unique bifunctional structure makes it a versatile intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with acetylene-linked architectures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and advanced materials with tailored properties.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and molecular recognition.
• Click Chemistry: The terminal alkyne group is highly reactive in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and material labeling.
• Organic Synthesis Building Block: Used in Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to construct complex organic frameworks.

Basic Information

Product Name	2-(4-Ethynylphenyl)Propan-2-Ol
CAS No.	66106-97-6
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	2-(4-Ethynylphenyl)-2-propanol; 1-(4-Ethynylphenyl)-2-methyl-2-propanol; 4-(2-Hydroxy-2-propyl)phenylacetylene; p-Ethynyl-α,α-dimethylbenzyl alcohol; 2-Methyl-2-(4-ethynylphenyl)propan-1-ol; 4-(1-Hydroxy-1-methylethyl)phenylacetylene
EINECS	Contact for details

Quality Control

Our 2-(4-Ethynylphenyl)Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.