Description

Phosphatidylcholine, L-α-Dipalmitoyl, [Choline-Methyl-3H] is a high-purity, tritium-labeled phospholipid essential for advanced biochemical and pharmacological research. This compound serves as a critical tracer molecule, enabling precise tracking and quantification of phosphatidylcholine metabolism, membrane dynamics, and drug delivery systems. It is primarily utilized by research institutions and pharmaceutical companies engaged in lipidomics, cell biology studies, and the development of liposomal formulations.

Application

• Biochemical Tracer Studies: Used as a radiolabeled probe for investigating phosphatidylcholine biosynthesis, turnover, and intracellular trafficking pathways.
• Membrane Biophysics Research: Essential for studying the structure, fluidity, and phase behavior of model lipid bilayers and biomembranes.
• Liposome & Drug Delivery Development: Acts as a key component and tracer in the formulation and stability testing of liposomal carriers for targeted drug delivery.
• Metabolic Pathway Analysis: Enables detailed kinetic studies of phospholipid metabolism in cell cultures and animal models.
• Autoradiography & Imaging: Provides a detectable signal for localization studies in tissues and cells using autoradiographic techniques.
• Enzyme Activity Assays: Serves as a specific substrate for assays measuring the activity of phospholipases and other lipid-modifying enzymes.

Basic Information

Product Name	Phosphatidylcholine, L-α-Dipalmitoyl, [Choline-Methyl-3H]
CAS No.	66030-24-8
Molecular Formula	C40H80NO8P (unlabeled parent compound)
Molecular Weight	734.04 g/mol (unlabeled parent compound)
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), [³H]; L-α-Dipalmitoylphosphatidylcholine, [choline-methyl-³H]; DPPC, [³H]-labeled; [Methyl-³H]-L-α-Dipalmitoylphosphatidylcholine; Tritiated DPPC; 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine (³H); Phosphatidylcholine, 1,2-dipalmitoyl, radiolabeled
EINECS	Contact for details

Quality Control

Every batch of our tritium-labeled Phosphatidylcholine is manufactured and handled under strict quality protocols to ensure radiochemical purity and specific activity consistency. We provide comprehensive Certificates of Analysis (COA) detailing radiochemical purity (typically >97% by HPLC), specific activity (e.g., Ci/mmol), chemical purity, and solvent composition. Our quality systems support research compliance, and material can be supplied with full regulatory documentation for use in regulated studies.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. Due to its sensitivity to oxidation and radiolytic decomposition, the material should be stored under an inert atmosphere (argon or nitrogen) and used promptly upon thawing. Follow all applicable laboratory safety guidelines for handling radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid or film (from solution)
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	30-100 Ci/mmol (Contact for exact value)
Chemical Purity (TLC/HPLC)	≥ 98%
Solvent	Toluene:Ethanol (9:1) or as specified
Concentration	1.0 mCi/mL (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.