Description

Cathepsin F is a lysosomal cysteine protease belonging to the papain superfamily, playing a crucial role in intracellular protein degradation and antigen processing. This enzyme is of significant interest in biochemical research for studying lysosomal function, protein turnover, and its implications in various disease pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science research sectors for target validation, assay development, and proteomics studies.

Application

• Biomedical Research: Used as a key reagent in enzymatic studies to investigate the role of cysteine proteases in cellular processes and disease mechanisms.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) assays to identify and characterize potential inhibitors for therapeutic intervention.
• Proteomics & Biochemistry: Serves as a model enzyme for studying protease specificity, kinetics, and protein-protein interactions within complex biological systems.
• Diagnostic Development: Potential use in the development of diagnostic kits and biomarkers related to lysosomal storage disorders or immune system dysregulation.
• Academic Research: Essential tool for university and institutional labs focusing on cell biology, immunology, and neurobiology research.

Basic Information

Product Name	Cathepsin F
CAS No.	65997-74-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cysteine protease F; CTSF; Cathepsin F (Homo sapiens); Lysosomal cysteine protease F; EC 3.4.22.41; Cathepsin F preproprotein; UNII-8V4Y9FQM8K
EINECS	Contact for details

Quality Control

Our Cathepsin F is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized for purity, specific activity, and stability, adhering to rigorous in-house specifications. A comprehensive Certificate of Analysis (COA), detailing assay results, purity profiles, and storage stability data, is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. For extended storage, consider under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE)	≥ 90%
Specific Activity	≥ XX units/mg protein
Protein Content (Bradford)	≥ XX %
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.