Description

1,25-Dihydroxydihydrotachysterol(3) is a synthetic analog of vitamin D, specifically engineered to modulate calcium and phosphate metabolism. This compound matters for its targeted biological activity, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily needed by manufacturers in the life sciences sector for producing reference standards, active pharmaceutical ingredients (APIs), and novel therapeutic agents targeting bone and mineral disorders.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of specialized vitamin D analogs and related therapeutic compounds.
• Research & Development: Used as a reference standard and biochemical tool in metabolic pathway studies, receptor binding assays, and pharmacological research.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral in the manufacturing process for drugs targeting osteoporosis, renal osteodystrophy, and hypoparathyroidism.
• Biochemical Studies: Employed to investigate the mechanisms of calcium homeostasis, cell differentiation, and proliferation.
• Analytical Standard: Serves as a high-purity calibrant for quality control laboratories using HPLC, LC-MS, or other chromatographic methods.

Basic Information

Product Name	1,25-Dihydroxydihydrotachysterol(3)
CAS No.	65878-49-1
Molecular Formula	C₂₈H₄₄O₃
Molecular Weight	428.65 g/mol
Synonyms	1,25-Dihydroxydihydrotachysterol3; Dihydrotachysterol3, 1,25-dihydroxy-; (5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; 1α,25-Dihydroxydihydrotachysterol; 1,25-DHDHT3; Vitamin D analog (1,25-Dihydroxy); Tachysterol derivative
EINECS	Contact for details

Quality Control

Our 1,25-Dihydroxydihydrotachysterol(3) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.