Description

Propanamide, n-(2-Bromophenyl)-2,2-Dimethyl- CAS NO 65854-92-4 is a specialized brominated amide derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a 2-bromophenyl substituent, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where the bromophenyl group imparts specific bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Research & Development: A versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transition metal-mediated transformations in academic and industrial labs.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands for asymmetric catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	Propanamide, n-(2-Bromophenyl)-2,2-Dimethyl-
CAS No.	65854-92-4
Molecular Formula	C11H14BrNO
Molecular Weight	256.14 g/mol
Synonyms	N-(2-Bromophenyl)-2,2-dimethylpropanamide; 2,2-Dimethyl-N-(2-bromophenyl)propanamide; 2-Bromo-N-neopentylaniline; α,α-Dimethyl-2-bromobenzeneacetamide; Propanamide, 2,2-dimethyl-N-(2-bromophenyl)-; N-(2-Bromophenyl)-2,2-dimethylpropionamide; 2-Bromo-N-(2,2-dimethylpropionyl)aniline
EINECS	Contact for details

Quality Control

Our Propanamide, n-(2-Bromophenyl)-2,2-Dimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.