Description

Phe-Nh2.Hcl CAS NO 65854-22-4 is a high-purity chemical intermediate, specifically a protected amino acid derivative. This compound is critical for advanced organic synthesis, offering a versatile building block for constructing complex peptide and pharmaceutical molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel active ingredients and specialty compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry for introducing specific amino acid sequences.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Protecting Group Chemistry: The HCl salt form provides stability for the amine group during multi-step synthetic processes.
• Research & Development: Essential for academic and industrial R&D in medicinal chemistry and chemical biology.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and advanced materials.

Basic Information

Product Name	Phe-Nh2.Hcl
CAS No.	65854-22-4
Molecular Formula	C9H12N2O2·HCl
Molecular Weight	216.66 g/mol
Synonyms	L-Phenylalaninamide hydrochloride; Phenylalaninamide HCl; (S)-2-Amino-3-phenylpropanamide hydrochloride; Phe-NH2·HCl; Fmoc-Phe-NH2·HCl (when protected); H-Phe-NH2·HCl; 2-Amino-N-(aminocarbonyl)-3-phenylpropanoic acid hydrochloride; Phenylalanine amide hydrochloride
EINECS	Contact for details

Quality Control

Our Phe-Nh2.Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.